前日 人気記事ランキング
153: 名無しさん 2022/03/16(水) 22:59:38.41
ラダーン倒した後ってどこ行くの?
砂漠に放り出されたんだけど

 

158: 名無しさん 2022/03/16(水) 23:01:00.10
>>153
フロムの広いエリアには何かあると思った方がいい
崖沿いに進むと行ける場所があるよ
ストーリー進めるなら隕石落ちたとこでも他の大ルーン取ってもいいけどね

 

162: 名無しさん 2022/03/16(水) 23:01:29.56
>>158
ありがとう

 

164: 名無しさん 2022/03/16(水) 23:01:54.99
>>153
一番奥の崖にある洞窟に向かう

 

173: 名無しさん 2022/03/16(水) 23:02:56.49
>>164
ありがとう

 

177: 名無しさん 2022/03/16(水) 23:04:25.27
>>173
周辺に祝福あるからまずはそこな。
近くにオオカミと大壺もいる

 

182: 名無しさん 2022/03/16(水) 23:04:58.20
>>173
壺には話しかけといた方が良いよ
俺は今めっちゃ後悔してる

引用元:https://pug.5ch.net/test/read.cgi/gamerpg/1647437762/

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    Introduction

    Types of Steroids

    Effects and Side Effects

    History and Usage

    # Contents

    ## Steroid
    Steroids are a class of organic compounds characterized by a specific type of chemical structure.
    They are primarily found in animals, plants, fungi, and some
    bacteria, where they play diverse roles in biological processes.

    Steroids have three interconnected rings, with functional groups such as hydroxyl or ketone groups attached
    to the molecule. Their structure is crucial for their activity, enabling them to
    act as hormones, vitamins, or other bioactive compounds.

    ## Page version status
    This page is based on content from Wikipedia and other reliable sources.
    It has been reviewed and updated by experts in the field.
    For more detailed information, please refer to the original source materials.

    ## Nomenclature
    The nomenclature of steroids refers to the systematic naming of these compounds.
    Steroids are named based on their structural features or biological functions.

    For example, "cholesterol" refers to a specific steroid molecule produced in the liver
    and used in animal cell membranes. Other examples include "sex hormones,"
    such as estrogen and testosterone, which are steroidal molecules involved in reproduction and endocrine regulation.

    ## Rings and functional groups
    Steroids have a unique structure with three interconnected rings.
    The core of the steroid framework consists of two
    cyclohexane rings fused together, forming a bicyclic system.

    Functional groups, such as hydroxyl (-OH) or ketone (C=O) groups, are
    attached to this framework and play a critical role in determining the biological activity of the
    molecule. These functional groups can influence steroid behavior,
    such as their affinity for specific receptors or their solubility in different environments.

    ## Naming convention
    The naming convention for steroids follows specific rules that help differentiate between the
    various types of steroidal molecules. The name often includes a prefix derived from the class
    of compounds (e.g., "sterol" for cholesterol, "keto" for ketone-containing sterols).
    Additional suffixes may indicate modifications or functional groups present on the molecule.
    This system ensures clarity and precision in communication within scientific communities.

    ## Species distribution
    Steroids are distributed across a wide range of species.
    Their presence is not limited to one type of organism, as they can be
    found in both eukaryotes and prokaryotes.
    For example:
    - **Eukaryotic organisms**: Steroids are abundant in animals, plants,
    fungi, and single-celled eukaryotes like protozoa.
    - **Prokaryotic organisms**: Sterols, a type of steroid, are found in bacterial cell membranes and play a role in maintaining membrane integrity.

    ## Eukaryotic
    In eukaryotic organisms, steroids serve various biological functions.
    For instance:
    - Animals produce a wide variety of steroids, including sex hormones (e.g., estrogen, testosterone) that
    regulate reproduction and metabolism.
    - Plants synthesize sterols as part of their cell membranes,
    contributing to the strength and structure of these cellular structures.

    - Fungi also produce sterols, such as ergosterol,
    which is essential for the integrity of fungal
    cell membranes.

    ## Prokaryotic
    In prokaryotic organisms, sterols are a key component of bacterial cell
    membranes. These sterols help maintain membrane fluidity and flexibility, ensuring that the cell can function under various environmental conditions.
    While sterols are common in bacteria and archaea, they are not typically found in other types of prokaryotes, such as viruses.

    ## Fungal
    Fungi produce a variety of sterols, including ergosterol,
    which is a fundamental component of fungal cell membranes.
    Ergosterol's structure differs slightly from cholesterol, the primary
    sterol in animals, but it serves similar functions in maintaining membrane
    integrity and facilitating the transport of ions and nutrients
    across the membrane.

    ## Plant
    In plants, sterols are essential for the structural integrity of cellular membranes.

    Unlike animals, plants do not synthesize cholesterol but instead produce a related molecule called phytosterol.

    Phytosterols share some structural similarities with animal sterols but have unique features that make them suited
    to plant biology. These compounds contribute to
    membrane stability and help regulate growth and development in plants.

    ## Animal
    Animals are perhaps the most complex users of steroids, producing a vast array of these molecules for various purposes.

    For example:
    - **Sex hormones**: Steroids such as testosterone (male) and estrogen (female)
    play critical roles in reproduction and sexual differentiation.
    - **Adrenal steroids**: The adrenal glands produce corticosteroids, which are involved in stress response and
    immune function.
    - **Vitamin D**: A steroid molecule derived from cholesterol that is essential
    for bone health and calcium absorption.
    - **Other sterols**: Cholesterol itself is a
    vital component of animal cell membranes and precursor to various hormones and other bioactive compounds.

    ## Types
    Steroids can be categorized based on their function or structure:
    - **By function**: Sex steroids (e.g., estrogen, testosterone), adrenal
    steroids (e.g., cortisol), vitamin D derivatives, and sterols like cholesterol.

    - **By structure**: Intact ring systems, cleaved rings,
    contracted rings, or expanded rings.

    ## Rings and functional groups
    The number and arrangement of rings in the steroid framework influence its biological activity.
    For example:
    - **Intact ring system**: Steroids with all three
    rings intact often retain their basic structural features,
    allowing them to interact with specific receptors and perform
    normal cellular functions.
    - **Cleaved rings**: Modified steroids where one
    or more rings have been broken or altered can result in compounds with different properties.
    These derivatives may be more effective at targeting specific
    cellular pathways or receptors.
    - **Contracted rings**: Steroids with one ring contracted into a smaller, often five-membered structure are
    common in certain hormones and signaling molecules.

    - **Expanded rings**: Some steroid derivatives have additional carbons added to the
    ring system, altering their shape and function.

    ## Biological significance
    Steroids are biologically significant compounds with diverse roles in organisms.
    They serve as signaling molecules, hormone precursors,
    and structural components of cell membranes. For example:
    - **Signaling**: Steroids can act as hormones, transmitting signals within and between cells to
    regulate gene expression and cellular activity.

    - **Vitamin D**: A steroid derivative that is essential for bone health and calcium absorption.
    - **Cholesterol**: A major component of animal cell membranes, which also serves
    as a precursor for sex hormones and other steroidal molecules.

    ## Biosynthesis and metabolism
    The biosynthesis of steroids involves complex biochemical pathways that convert simple precursors into highly structured molecules.

    The two primary pathways for steroid synthesis are the
    Mevalonate pathway (also known as the cholesterol
    biosynthesis pathway) and the alternative pathways, such as
    the reverse transport of sterols in cells.

    ### Mevalonate pathway
    The Mevalonate pathway is a series of enzymatic reactions that convert acetyl-CoA into mevalonic acid, which
    serves as a precursor for the synthesis of
    cholesterol and other steroids. This pathway is active in most animals and plays a critical
    role in maintaining cellular health and homeostasis.

    ### Steroidogenesis
    Steroidogenesis refers to the process by which sterols are synthesized and modified into biologically active
    molecules. For example, cholesterol can be
    converted into vitamin D in sunlight, or transformed into sex hormones like estrogen and testosterone.
    This process is tightly regulated by the body to ensure that steroid levels remain within a healthy range.

    ### Alternative pathways
    In addition to the Mevalonate pathway, alternative pathways for steroid biosynthesis exist,
    particularly in certain tissues and organisms. These pathways may involve different precursors
    or unique enzymatic modifications, allowing for the production of specialized sterols tailored to specific biological needs.

    ### Catabolism and excretion
    Once steroids have fulfilled their biological function, they are broken down by enzymes known as steroid
    sulfatases and sulfotransferases. This process, known as catabolism, converts the steroids into inactive metabolites that
    can be safely excreted from the body. The excretion of sterols is a critical step in maintaining
    homeostasis and preventing the buildup of potentially harmful levels of these molecules.

    ## Isolation, structure determination, and methods of analysis
    The isolation and structural determination of steroids are essential for understanding their
    biological roles and developing new therapies. Techniques such as chromatography, mass spectrometry, and nuclear magnetic resonance
    (NMR) spectroscopy are commonly used to isolate and analyze steroidal
    compounds. These methods allow researchers to identify unknown steroids or study the
    structure of known molecules in detail.

    ## Chemical synthesis
    The chemical synthesis of steroids involves the use of organic chemistry techniques
    to construct these molecules from simpler precursors.

    While natural methods dominate in biological contexts, synthetic approaches have been developed for the purposes of research and drug
    development. Synthesis can be challenging due to the complexity of the steroid framework,
    but advanced methodologies have made it possible to create sterols with
    specific structural modifications.

    ### Precursors
    The synthesis of steroids begins with precursors
    such as mevalonic acid or isopentenyl pyrophosphate (IPP),
    which are derived from acetyl-CoA. These compounds undergo a series of enzymatic reactions to
    produce the steroid nucleus, the core structure of all sterols.

    ### Semisynthesis
    Semisynthesis involves the chemical manipulation of naturally occurring
    steroids or their derivatives to create new molecules with desired properties.
    This approach is particularly useful for modifying existing sterols to enhance their biological activity or
    improve their pharmacokinetics.

    ### Total synthesis
    Total synthesis refers to the de novo construction of steroids from
    non-steroidal precursors, without relying on natural sources.

    This method is often used in drug discovery to create molecules with therapeutic potential.
    The challenge lies in replicating the complex structure and
    biological activity of naturally occurring sterols.

    ## Research awards
    Over the years, significant research has been conducted
    into the chemistry, biology, and applications of steroids.
    Notable scientists in this field have received awards for
    their contributions to understanding steroid metabolism, biosynthesis,
    and function. These achievements have led to advancements in fields such as medicine, nutrition, and
    pharmacology.

    ## See also
    - **Lipid metabolism**
    - **Endocrinology**
    - **Biochemistry**

    ## References
    This article is based on publicly available information and does not constitute medical
    advice. Always consult a healthcare professional for medical
    concerns or before starting any new treatment regimen.

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    Moreover, seek the guidance of with healthcare professionals or skilled health advisors
    to ensure Anavar aligns along with your objectives,
    overall health, and particular person circumstances. Anavar (Oxandrolone) is a popular anabolic steroid
    known for its potential to deliver important outcomes when it comes to muscle definition, strength enchancment, enhanced
    endurance, and fats loss. When used responsibly and as a part of a well-rounded health routine, Anavar might help individuals achieve their desired
    physique and performance goals.
    Combining Oxanivar with other steroid dietary supplements will drastically speed up and maximize your gains.
    For onerous gainers, stacking Oxanivar with other compounds,
    strongly beneficial. Var utilized in muscle constructing, slicing, and strength stacks, however it's not for bulking.

    Var, most frequently used when you want to lose fats while
    adding lean muscle, and enhancing strength.
    An Anavar cycle is an efficient way to improve efficiency, build
    lean muscle, and lose fat whereas minimizing the danger of unwanted effects.

    When used correctly, Anavar can provide vital advantages, particularly together with different steroids
    like Winstrol. Nevertheless, earlier than embarking on an Anavar cycle, it’s important to know the potential dangers, proper dosages,
    and cycle size.
    To sidestep potential unwanted effects, it's important to adhere
    to the recommended dosage and thoroughly monitor particular person reactions.
    Anavar’s recognition is underscored by the ability for people to legally buy the
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    Anavar’s delicate nature makes it female-friendly, and ladies usually discover
    PCT pointless as a end result of its light influence on hormonal stability,
    especially with reasonable doses and shorter cycles. The body’s pure equilibrium can typically restore itself post-cycle, contemplating the
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    Perfect for chopping cycles, it maintains muscle mass whereas selling fats loss.
    Suitable for each men and women, this gentle but efficient anabolic is trusted by athletes for its safety and consistent outcomes.

    Anavar has a powerful anabolic ranking, yet at the identical
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    steroids are. Whereas it could possibly contribute to
    bulking with high-quality weight gain6 with out water retention, Anavar is strongest for cutting and
    enhancing athletic performance. Ladies who use Anavar will, nevertheless, discover that it
    may possibly add spectacular lean muscle gains to the physique, and this is the
    principle anabolic steroid that is suitable for girls to make use of for this objective.
    Oxanabol, delivered to you by Alpha Pharma, has established itself as a frontrunner within the anabolic steroid market, paving the best way for athletes and bodybuilders to achieve
    their fitness aspirations.
    Read about how celebrities use steroids and their favorites by clicking the link under.
    You may be surprised to be taught that anabolic steroids
    are frequently employed in typical medication to effectively deal
    with a myriad of illnesses. For this cause, we now have made a complete guide to assist folks such as you buy Anavar on-line without falling sufferer to all the untrustworthy individuals flooding the net.
    Anavar (Oxandrolone) is your ultimate partner for sculpting
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    The underground market is rife with counterfeit or substandard products,
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    Buying Anavar on-line provides convenience, but it requires vigilance to ensure the product's safety and legality.
    Taking the best precautions may help you keep away from counterfeit gadgets and unreliable
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    For those in search of Anavar within the USA, compliance with federal and state rules is paramount.

    An essential factor to assume about when planning your Anavar stack is the numerous advantage of its
    lack of water retention as a result of it doesn’t convert
    to estrogen. You can use this by stacking it with other compounds that don’t aromatize, like Trenbolone and Masteron. Such a stack can effectively have you ever
    not having to consider fluid retention in any respect except you determine to take a higher dose of testosterone in the stack.
    Few steroids could have us intently looking at both male
    and female cycles, but Anavar is an exception.
    This is due to water filling contained in the
    muscle cell and fluid being expelled outdoors the muscle
    cell. Consequently, as extracellular water is now not obscuring superficial veins,
    they turn into more visible. Liver injury shouldn't be
    discounted as a attainable side impact of Anavar, particularly if excessive doses are administered for extended durations.
    Loopy Bulk's formulation are supported by scientific research and are
    safe for men and women to make use of. Alternatively,
    they could decide to stack the above steroids along side
    Anavar. We have discovered Olympus Males to be essentially the
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    Girls generally require decrease dosages, starting from
    5-20 mg per day, to reduce the chance of virilization (development of male characteristics) and other unwanted effects.

    It is commonly considered one of many more female-friendly anabolic steroids because of its decrease androgenic properties and decreased risk
    of virilization compared to other choices. Flex Lewis, a distinguished bodybuilder and multiple-time Mr.
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    His advocacy extends past personal utilization, as he emphasizes the significance of obtaining Anavar from reliable sources for
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    as a valuable tool in attaining lean muscle gains with out compromising health.

    It exhibits potent anabolic properties with minimal androgenic effects, making it
    a fascinating option for lots of. Anavar functions by binding to androgen receptors
    in the body, stimulating protein synthesis and enhancing nitrogen retention throughout the muscles.
    This results in increased muscle growth, improved strength,
    and enhanced athletic performance. In conclusion, Anavar is a popular anabolic steroid among both male and female customers as a end result of its relatively gentle nature and decrease threat
    of unwanted side effects in comparison with different steroids.

    However, it is important to strategy its use with caution and under the guidance
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    traits of Anavar®, the most important revolve round its
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    lower SHBG and inhibit glucocorticoid hormones.

    Docs would prescribe it to people wanting bigger muscle tissue, extra strength, or to burn extra fat.

    Finasteride (Propecia) is an FDA-approved medicine shown to be efficient at blocking DHT levels in the physique and lowering
    hair loss (19). Nevertheless, studies present that roughly 52% of
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    using Finasteride. Thus, taking this treatment may counteract the anabolic results of Anavar, inflicting bodybuilders to be
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    References:

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  44. Felipa より:

    The addition of some other very highly effective compounds is going to take your mass
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    shall be ramped up in this cycle without water retention attributable to any of the compounds.
    Testosterone is also included to offer a functional degree of the hormone.
    Parabolan can be utilized at up to 300mg weekly, and Winstrol oral at 50mg every day
    most.
    If you’re a fairly normal dude, these mental results are solely more probably to be
    mild; making Tren very manageable. As A Result Of your blood pressure rises
    on Tren, it additionally makes endurance-based exercise/cardio more
    difficult, as your blood isn’t flowing as efficiently.
    As a results of this change, your precise body temperature may also increase.
    This is why you'll be able to really feel hotter and begin to sweat more than usual (particularly
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    You’ll acquire plenty of muscle and get ripped to shreds…assuming you're employed hard in and out
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    With this info, you'll be better equipped to make an knowledgeable determination about which steroid
    best aligns along with your private health objectives and requirements.

    For the off season athlete there are very few if any anabolic steroids that can promote quality construct ups and lean tissue like trenbolone acetate.
    Additional as the steroid doesn't aromatize it will not
    promote water retention. More importantly due to instability to reinforce the metabolic
    rate, less fats accumulation will happen during the period of growth.

    Trenbolone’s androgenic properties can accelerate
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    Sustanon and Trenbolone are usually not recommended for feminine use as a end result of
    their robust androgenic properties. These compounds
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    Girls excited about efficiency enhancement ought to explore alternative compounds with milder androgenic
    profiles. Cycling patterns and duration play a
    vital function in optimizing the advantages of Sustanon and Trenbolone whereas
    managing potential dangers.
    Enigma Laboratories as soon as manufactured the trenbolone hormone as a human grade anabolic
    steroid in the form of paraboloan. Parabolan is comprised of the same trenbolone hormone present in trenbolone acetate
    except on this case it is hooked up to the larger hexa hydro benzyl carbonate ester.
    With the explosion of underground labs in the 1990’s, this steroid would emerge as probably the most highly wanted anabolic steroid of
    all time by quite a few physique minded people.
    The trenbolone hormone, structurally altered type
    of the nandrolone hormone, altered by the addition of a
    double bond at the carbon 9 and 11 position. In terms
    of oxygen utilization, Trenbolone has been shown to extend purple blood cell depend, boosting oxygen supply to muscle tissue during exercise.

    This plays a significant position in bettering general endurance, efficiency, and muscle
    progress.
    Different anabolic steroids, corresponding to Dianabol, Winstrol, and Anavar, may even pose fewer risks; however, as a
    result of their oral nature, they will trigger extra irritation within the liver.
    When considering stacking tren with other supplements or steroids, it is necessary to consult with a healthcare professional or a educated coach.
    They can present steerage on potential interactions, dangers, and advantages to guarantee
    security and effectiveness.
    In this case, one other steroid could additionally be simpler than trenbolone, not by method of potency but because sleep
    is vital for optimal body composition. It is essential to observe levels of cholesterol whereas utilizing these steroids to forestall potential cardiovascular dangers.
    While both Anavar and Trenbolone have fats loss properties, Trenbolone is considered the stronger of the two because
    of its capability to promote each fats loss and muscle building concurrently.
    Nevertheless, you will want to note that Trenbolone can be recognized for its
    strong androgenic effects, which can cause androgenic unwanted aspect effects in some customers.
    Trenbolone, however, is a more potent steroid that is derived from Nandrolone.
    It was first developed within the late Sixties and is thought for its
    capability to extend muscle mass, strength, and endurance.

    There are a number of factors presently impacting its use in bodybuilding and fitness, and the lengthy run seems to be very thrilling for
    those who have an interest in this complement. Trenbolone is a robust anabolic
    steroid that has been used by bodybuilders and athletes to build muscle, increase energy,
    and improve athletic efficiency. Tren, brief for trenbolone, is an anabolic steroid utilized
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    resulting in increased protein synthesis and nitrogen retention in muscles.

    This ends in accelerated muscle growth, improved feed effectivity, and enhanced
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    While Anavar and Trenbolone have completely different chemical buildings,
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    This prompts the androgenic pathway, which leads to a rise in protein synthesis, muscle mass, and energy.
    Anavar has a lower binding affinity to androgen receptors in comparison with Trenbolone, which may explain why it is
    less potent. However, Anavar can be much less prone to cause
    androgenic unwanted aspect effects like acne, hair loss, and prostate enlargement.
    Anavar is taken into account to be a milder various to Trenbolone
    with fewer unwanted facet effects.
    Long-term use can also pose risks to cardiovascular well being
    and hormone levels. Given these negative results, anybody taking trenbolone should pay
    consideration to the potential for cardiac harm and work closely with
    their physician to mitigate these risks. Nevertheless, trenbolone is a robust hormone with potential unwanted facet effects, so it should
    only be used under the supervision of a medical skilled.
    Additionally, trenbolone has been proven to improve the quality of RBCs, making them extra environment friendly at carrying oxygen.
    Whereas trenbolone is most commonly used to deal with anemia, it could even be
    used to improve athletic efficiency by growing oxygen uptake.

    References:

    Steroids Sports (https://Www.Google.Co.Uz)

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