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307: 名無しさん 2023/08/17(木) 16:19:26.37
技量剣士で鋭利ツヴァイ使ってるけど、両手持ちで表示火力10しか上がらないのに片手と比べて100以上ダメ上がるのなんでなん…
310: 名無しさん 2023/08/17(木) 16:21:41.27
>>307
モーション値
311: 名無しさん 2023/08/17(木) 16:22:33.59
>>307
モーション値の違いってやつだな
313: 名無しさん 2023/08/17(木) 16:33:55.83
>>307
特大系は両手持ち地上攻撃のモーション値が高い
314: 名無しさん 2023/08/17(木) 16:53:49.47
>>310、311、313
ありがとう。ググっても出てこないけど筋力1.5倍された表示火力+武器種毎に固有の倍率が付与されているってことかな
315: 名無しさん 2023/08/17(木) 17:10:05.23
>>314
そういうことやね
ブラボの頃は物によっては0.7倍とか極端な倍率があって表示攻撃力しか見てない人が騙されてたが、
ダクソ3ではそこまで極端な物はなくなってた印象
319: 名無しさん 2023/08/17(木) 17:40:21.56
>>314
武器種ごとというか特大系とそれ以外で分かれてる感じ

引用元:https://pug.5ch.net/test/read.cgi/gamerpg/1692086541/

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    Some research in mouse fashions suggest that myostatin inhibition may stop cancer-related muscle loss in both lung
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    The inhibitory position performed by MSTN in muscle improvement has made it an essential therapeutic goal for accelerating muscle mass.
    There are several ways of disrupting MSTN exercise starting from the use of MSTN antibodies to natural compounds.

    Detailed data of those strategies and the
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    In contrast, the gastrocnemius confirmed histological proof of
    losing with suspension that was partially mitigated with myostatin inhibition. Whereas expression of genes
    related to protein degradation (Atrogin-1 and Murf-1) within the tibialis anterior increased with suspension, these atrogenes weren't
    significantly decreased by myostatin inhibition despite a modest activation of the Akt/mTOR pathway.
    Taken collectively, these findings recommend that myostatin is essential in hindlimb suspension but in addition motivates
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    The authors of this text will make the uncooked knowledge supporting their conclusions obtainable,
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    The impact on skeletal muscle development is likely
    one of the major reasons for the large curiosity for epicatechin in recent years.
    One examine was able to determine that epicatechin from dark candies inhibits myostatin. Low levels of myostatin protein are desirable because it leads to increased capability to build skeletal muscle mass.
    Phenolic compound resveratrol has anti-inflammatory and antioxidant properties
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    As a end result, it could hinder the degradation of proteins, which is
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    routes, and phorbol ester by way of minimizing the expression of MAFbx,
    MuRF1, and NF-κB [190]. Moreover, elevated NRF2 gene expression has
    been linked to the regulating of pro-inflammatory cytokines, primarily IL-6 and TNF.

    The number of myostatin-positive SC–myostatin inhibits the progress of SC into the S phase of the cell cycle [9]–increased after 2 weeks of immobilization in each groups.

    More studies are wanted to determine the connection between disuse-atrophy and
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    may have an impaired myogenic capacity compared to younger [34].

    In vitro studies have shown that like FST, FLRG binds to activin and BMPs to
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    In wholesome older men, lower serum MSTN ranges had been linked
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    It can be evident that serum MSTN does not differ in young and sarcopenic elderly males (Ratkevicius et al., 2011).

    When activated, MSCs undergo uneven division during muscle regeneration to give
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    and entry into differentiation (Zammit et al., 2004).
    Collectively, the transcriptional community regulates the development of the MSC lineage from origin to myogenic specification, differentiation, and fusion to provide myoblasts.
    This variability factors to an intricate interplay between myostatin and different regulatory methods within the body,
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    Ecklonia Cava is a type of brown algae that is high in antioxidants and has been proven to inhibit myostatin.
    One Other talked-about technique of inhibiting myostatin is thru the
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    In each humans and animals, myostatin is a hormone that
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    Nonetheless, Welle did mention some unwanted aspect effects within the mice come the
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    This disparity in MSTN availability could contribute to
    a shift in efficiency between species. A pharmacokinetic
    study with MYO-029 found that the focus of MYO-029 required to elicit a 50% improvement in muscle mass in monkeys
    was 18 instances greater in comparability with the same improvement in mice [107].
    This discrepancy in pharmacokinetics and MSTN serum concentration between diseased
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    Myostatin is known to signal via transmembrane activin Kind IIB receptors
    (ActRIIB) along with Activin A and other ActRIIB ligands28,34.

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    It is conceivable the combination of flavonols and phytochemicals found in pure cocoa might have
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    of (–)-epicatechin supplementation worthy of further research is the timing and period of supplementation.
    Instead of chronic supplementation, it could prove beneficial to
    look at using (–)-epicatechin when supplemented instantly prior to exercise.

    Studies have proven (–)-epicatechin increases blood circulate through vasodilation by
    the use of nitric oxide manufacturing (3). Lastly, the potential inhibition of aerobic adaptations in skeletal muscle as a end result of the antioxidant properties of (–)-epicatechin have to
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    Ever since its discovery, intensive analysis has been conducted to
    suppress the exercise of MSTN using soluble activin sort IIB (sACVRIIB) receptors, peptides or propeptides, small molecules, neutralizing antibodies,
    or MIPs (Table 1). Based in Canada, Katrina is an skilled
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    The samples have been then centrifuged at 3000 rpm for 10 min at 4 °C to gather the supernatant.

    The levels of the neurotransmitters acetylcholine (ACh), glutamate
    (Glu), gamma-aminobutyric acid (GABA), and serotonin (5-HT), that
    are associated to fatigue, have been measured utilizing ELISA following the manufacturer’s directions.
    The absorbance at 550 nm and 340 nm was measured using a spectrophotometer or microplate reader.
    The kits used on this research have been evaluated for consistency of efficiency throughout totally different batches of
    kits by restoration exams with recoveries starting from
    90%-110% and calibrated by requirements. The
    gear used had a measurement accuracy of zero.01% and was calibrated
    earlier than every experiment. Ltd. (Wuhan, China),
    and cultured in DMEM supplemented with 10% FBS and 1% penicillin/streptomycin (Cell-specific DMEM; Procell, Wuhan, China) in an incubator
    at 37 °C with 5% CO2.
    Cell recoveries of MIF1- (22%) and MIF2-treated (22%) C2C12 cells have been better than those of non-treated cells (Figure 3A).
    To investigate the results of MIF1 and MIF2 on myogenic differentiation,
    70% confluent cells were switched from development medium to myogenic
    differentiation medium supplemented with MIF1 or MIF2 and incubated for 3 days.
    Myotube formation was increased for MIF1- (4%) or MIF2- (12%) handled cells than for non-treated controls (Figure 3B).
    Myosin heavy-chain (MYH) mRNA expression was
    increased and MSTN mRNA expression was decreased in MIF1-treated
    cells, whereas MSTN mRNA expression in MIF2-treated cells and non-treated controls were comparable.
    MYOD, MYOG, myosin light-chain 2 (MYL2), and MYH proteins expression have been elevated
    in MIF1- or MIF2-treated cells, whereas MSTN protein expression increased in MIF1-treated cells however not
    in MIF2-treated cells (Figure 3C,D).
    It also phosphorylates and inhibits Forkhead field O1 (FoxO1), which is a transcription issue that represses GLUT4 gene transcription [131].
    MSTN inhibition upregulates the PI3K/Akt pathway, leading to a
    rise expression of GLUT4 [132, 133]. Additionally,
    MSTN inhibits the activation of adenosine monophosphate-activated protein kinase (AMPK), an important regulator of mitochondrial biogenesis and power metabolism, which additionally promotes GLUT4 translocation in response to insulin-independent energy stress [129, 134].
    Furthermore, MSTN knockout has been reported to upregulate adiponectin, a regulator of adipocyte energy metabolism that improves insulin sensitivity
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    food regimen, while maintaining regular levels of blood insulin, resistin, and leptin [121].
    The mouse hindlimb suspension (HS) model mimicked many of the changes that
    occur with spaceflight-induced muscle atrophy and loss
    of function3,43,forty nine,50.
    Whereas the well being benefits of epicatechin and other antioxidants found in tea leaves, coffee beans,
    and cocoa beans are innumerable, the ergogenic results of isolated epicatechin remain considerably equivocal [1].
    Current proof also raises doubts about the utilization of myostatin blockers
    for building muscle mass and preventing muscle atrophy in people [2].
    It appears to me that if the muscle weak spot is a perform of muscle mass wastage then there is a correlation between myostatin inhibition and enhancements in muscle strength, largely because of the rehabilitation of muscle tissue.
    Studies investigating the effects of myostatin inhibition have proven that there's more than likely a resultant improve in muscle
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    In old mice, daily injections of epicatechin led to elevated overall muscle
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    Most individuals who take resistance coaching critically most likely already take 2 if
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    coaching.
    The serum from the remaining separation tube
    was separated, labeled, and saved in micro centrifuge tubes
    at -80°C for later analysis. Following completion of the study, samples have
    been analyzed for lively testosterone, free testosterone, and cortisol with an enzyme immunoassay (EIA)
    assays utilizing Goat-Anti-rabbit IgG (GARG) coated
    microplates. Assays have been performed using a Jitterbug microplate shaker
    (Boekel Scientific-Philadelphia, PA) and a Tricontinent Multiwash Advantage microplate washer
    (Grass Valley, CA).
    Two molecules are epimers of each other after they have no much less than two uneven carbon atoms however differ by
    configuration at solely a type of carbons.
    Primarily, epimers are equivalent molecules with the identical asymmetric carbon atom (and its bonds) rotated in a special way in space (see
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    The supplements had been provided pre-mixed into
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    Epicatechin is a pure plant compound from a powerful group
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    As a natural anabolic compound, laxogenin stacks properly with epicatechin to boost muscle progress.
    Two serum separation vacutainer tubes and one
    EDTA vacutainer tube was obtained from every subject. The serum vacutainers had been separated through centrifugation a 6,000 rpm for 20 minutes.
    One serum separation tube and the EDTA tube were sent to Quest Diagnostics (Dallas, TX) for assay of
    a normal clinical chemistry profile and entire blood cell counts to make
    sure security of supplementation in the course of the protocol.

    Therefore how some myostatin inhibor dietary supplements are receiving
    poor critiques on-line with clients complaining that they didn’t notice a thing.
    Now, to turn out to be one of the best bodybuilders in the world like Flex, you’ve obtained to have
    beyond exceptional genetics, use anabolic steroids and practice hard in the
    health club for a very long time. In my opinion, the gathering of blood samples solely on days 14 and 28 should be clearly said as a limitation of the manuscript.

    Standardize the writing of the names of study phases all through the manuscript
    – generally capitals are used as a first letter of the name
    of the phases, and in the other components of the manuscript lowercase is used.

    Myostatin inhibition did not result in any measurable increase in Akt activation, which is an upstream regulator of FoxO transcription factors65,sixty
    six, nor did it lead to an increase in p-p70s6K/p70s6K, which
    signifies increased protein synthesis31. It is noteworthy that the expression of those proteins was measured in the TA, which showed the most strong response to myostatin inhibition. Yet in HS, this muscle is subjected to continual stretch which is hypertrophic in immobilized limbs67.

    Evaluating a shortened muscle (e.g., the gastrocnemius) would have been informative; however, we've previously proven similar expression of
    atrogenes in each the TA and gastrocnemius after 14 days of HS.

    Members engaged in four cycling train classes per week for four weeks
    for a total of sixteen classes (Table 2). Periods one and three of every week
    were completed independently at the College of South Alabama Recreation Center using the prescribed intensity and
    duration and completion of every session was reported to review personnel.
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    Louis, MO).
    Complete RNA concentration was determined spectrophotometrically
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    (OD) at 260 nm utilizing an OD260 equal to forty
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